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LiverCare™ (120 caps)

LiverCare™ (120 caps)
gluten free vegetarian vegetable capsule Non GMO Supplement

Synergistic blend of standardized herbal extracts and potent antioxidants that support liver health

  • Enhances fat metabolism within the liver
  • Promotes glutathione synthesis
  • Supports gastric, colon and liver cell functions
  • Optimizes liver cleansing and toxin filtering activities
  • Promotes safe elimination of toxins

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Product Information Sheet (PDF)

Patient Brochure (PDF)

Unique Properties

With the high incidence of toxic chemicals in our environment, food, water, medications and even body tissues, some individuals experience an accumulation of harmful compounds in their bodies. A concentration of such substances can lead to a variety of metabolic dysfunctions, particularly to the immune, neurological and endocrine systems of the body. Additionally, fat build up in the liver can lead to liver damage. Patient One LiverCare™ is a synergistic blend of antioxidants, nutrients, and herbs that enhance the body’s ability to detoxify and protect the liver. This unique combination aids in fat metabolism within the liver, promotes glutathione synthesis, supports the safe elimination of toxins and supplies antioxidants to help reduce free radical damage.

Increasing intake of water / fluids while using this product is recommended. Prior to embarking on a detoxification program, it is also important to achieve optimal bowel function. Therefore, we recommend using a fiber formula such as Patient One C-Cleanse as it supports the elimination of toxins from the body, binding toxins released into the intestines from the liver and preventing their reabsorption.

Key Ingredients

Milk Thistle Extract:

A common herb native to the Mediterranean, milk thistle has been broadly used for its nutritional support of liver function for two centuries. Seeds of the dried milk thistle flower are rich in silymarin, a bioflavonoid complex of silybin, silydianin, and silychristin. Silymarin protects the liver from free radical damage, supports glutathione concentrations and promotes superoxide dismutase activity. Milk thistle extract also stimulates protein synthesis in hepatic cells.

Vitamin C:

Vitamin C aids the detoxification process by limiting damage to the body from free radicals. Vitamin C strengthens the immune system and is especially effective in helping the body rid itself of heavy metal toxins like mercury, lead, cadmium and nickel. 

Selenium:

Selenium is a trace mineral with an important role in detoxification. It is a cofactor for the production of glutathione peroxidase, a form of glutathione that enhances antioxidant protection against free radical damage. Selenium assists in the detox of heavy metals by enhancing the activity of lymphocytes and macrophages.

L-Glutathione:

Glutathione plays critical roles in protecting cells from oxidative damage and maintaining redox homeostasis. It is the most important low molecular weight antioxidant synthesized in cells. As a reducing molecule, glutathione reacts with oxygen species by neutralizing the unpaired electrons that make them highly reactive and dangerous. Over-production of reactive oxygen species impairs the intracellular glutathione homeostasis, leading to deficiency, a pathophysiological marker in alcoholic and non-alcoholic liver diseases. Evidence from experimental research and previous clinical studies shows glutathione administration appears a promising strategy to recover oxidative stress-induced liver damage.

Alpha Lipoic Acid:

An antioxidant that boosts tissue glutathione levels, α-lipoic acid (ALA) also plays a role in binding heavy metals. Insulin resistance, oxidative stress, inflammation and innate immune system activation contribute to the development of non-alcoholic fatty liver disease through steatosis and inflammation in the liver. ALA has been shown to improve insulin sensitivity and suppress inflammatory responses. ALA has been shown to improve liver antioxidative capacity by increasing total superoxide dismutase, manganese SOD, and copper/zinc-SOD activity as well as glutathione content. 

Dandelion Root:

Dandelion root has been studied for its protective effects on the liver, specifically protecting the body against cellular damage and abnormal growths caused by toxic chemicals. Used in traditional Chinese medicine for a variety of health benefits, dandelion contains protective flavonoids that have been shown to have a capacity to scavenge free radicals, sequester metal ions, and reduce the breakage of supercoiled DNA strands induced by hydroxyl free radicals. 

Artichoke:

Artichoke extract aids the digestive process by promoting healthy bile flow and intestinal motility, reducing toxin exposure in the gut. It also supports hepatic cell function and blood flow in the liver. Studies have shown antioxidative and protective properties against oxidative stress in animal hepatocytes. Also, it has shown to provide protection of lipoprotein from oxidation and inhibition of hemolysis in vitro.

BroccoSinolate® Broccoli Extract:

Broccoli sprouts are a rich source of glucosinolates and isothiocyanates that induce phase 2 detoxication enzyme and boost antioxidant status. Glucosinolates are hydrolyzed by myrosinase (an enzyme found in plants and bowel microflora) to form isothiocyanates. BroccoSinolate® ingredients were developed to capitalize on the health benefits of glucosinolates. 

Turmeric Extract:

Studies of plant phytochemicals and their potential beneficial effects on liver and digestive tract functionality has shown artichoke, dandelion, and particularly turmeric have notable antioxidant activity. The combined actions of curcumin and silymarin include enhancing phase 2 detoxification enzymes, supporting glutathione synthesis and promoting gastric, colon and liver cell functions. 

Bioperine® Black Pepper Extract:

LiverCare includes Bioperine®, a patented extract derived from the common black pepper fruit that contains the alkaloid piperine. Black pepper has been shown to enhance the bioavailability and promote absorption of turmeric curcumin, as well as Vitamin C and selenium, both in pre-clinical studies and in studies on human volunteers.

 

References

  1. Sacco R, e. (2016). Glutathione in the treatment of liver diseases: insights from clinical practice. - PubMed - NCBI. [online] Ncbi.nlm.nih.gov. Available at: https://www.ncbi.nlm.nih.gov/pubmed/27603810 [Accessed 27 Dec. 2018].
  2. Jung, T. S., Kim, S. K., Shin, H. J., Jeon, B. T., Hahm, J. R. and Roh, G. S. (2012), a-lipoic acid prevents non-alcoholic fatty liver disease in OLETF rats. Liver Int, 32: 1565-1573. doi:10.1111/j.1478-3231.2012.02857.x
  3. Stankovi, M. N., Mladenovi, D., Ninkovi, M., Ethurii, I., Sobaji, S., Jorgaevi, B., de Luka, S., Vukicevic, R. J., … Radosavljevi, T. S. (2014). The effects of a-lipoic acid on liver oxidative stress and free fatty acid composition in methionine-choline deficient diet-induced NAFLD. Journal of medicinal food, 17(2), 254-61.
  4. Antioxidant, Prooxidant, and Cytotoxic Activities of Solvent-Fractionated Dandelion (Taraxacum officinale) Flower Extracts in Vitro
  5. Chun Hu and and David D. Kitts* Journal of Agricultural and Food Chemistry 2003 51 (1), 301-310 DOI: 10.1021/jf0258858
  6. Analysis of Antioxidative Phenolic Compounds in Artichoke (Cynara scolymus L.) Mingfu Wang,†, James E. Simon,*,†, Irma Fabiola Aviles,†, Kan He,§, Qun-Yi Zheng,§ and, and Yaakov Tadmor† Journal of Agricultural and Food Chemistry 2003 51 (3), 601-608 DOI: 10.1021/jf020792b
  7. Menghini, L., Genovese, S., Epifano, F., Tirillini, B., Ferrante, C., & Leporini, L. (2010). Antiproliferative, Protective and Antioxidant Effects of Artichoke, Dandelion, Turmeric and Rosemary Extracts and Their Formulation. International Journal of Immunopathology and Pharmacology, 601–610. https://doi.org/10.1177/039463201002300222
  8. Chemoprotective Glucosinolates and Isothiocyanates of Broccoli Sprouts Theresa A. Shapiro, Jed W. Fahey, Kristina L. Wade, Katherine K. Stephenson and PaulTalalay Cancer Epidemiol Biomarkers Prev May 1 2001 (10) (5) 501-508;

Supplement Facts

Serving Size: 2 Capsules
Servings Per Container: 60
Amount Per Serving % Daily Value**

Vitamin C (as ascorbic acid)

200 mg 222%

Selenium (as L-selenomethionine)

100 mcg 182%
L-Glutathione 100 mg
Alpha Lipoic Acid 150 mg
BroccoSinolate® Broccoli Extract

(Brassica oleracea) (stems and buds) [Standardized for 4% glucosinolates (6 mg)]

150 mg
Milk Thistle Extract

(Silybum marianum) (seeds) [Standardized for 80% silymarin (112 mg)] 

140 mg
Dandelion Root

(Taraxacum officinale)

100 mg
Artichoke

(Cynara scolymus) (leaf) 

100 mg
Turmeric Extract

(Curcuma longa) (rhizome) [Standardized for 95% curcuminoids (95 mg)]

100 mg
Bioperine® Nature's Thermonutrient

(Piper nigrum) (fruit) [providing 95% piperine (2.85 mg)]

3 mg
† Daily Value not established.
** Daily Values are based on a 2,000 calorie per day diet.


Suggested Use

Take 2 capsules each morning on an empty stomach as a dietary supplement or as directed by a qualified health care professional. Increasing water / fluids intake is recommended to support the elimination of toxins from the body.

Warnings

Pregnant or nursing women should not use this product. If you are taking diuretics or any other medications, consult your doctor before use. Discontinue use and consult doctor if any adverse reactions occur. Milk thistle and artichoke should be avoided by individuals with allergies to members of the aster (Compositea/Asteraceae) family, daisies, artichoke, kiwi or thistle. Some ingredients may cause gastrointestinal discomfort in certain individuals. Some studies have reported that milk thistle, curcumin and broccoli sprout extract can affect the way that the liver breaks down medications metabolized by the cytochrome P450 system, altering the effects of these medications and possibly the dose needed for treatment.

 
LiverCare™ (120 caps) Label