Patient One formulated Cholest-Plex to be a gentle, well-tolerated natural formula for maintaining cholesterol levels already within a normal range. Cholest-Plex provides a complementary combination of evidence-backed natural ingredients for healthy lipid maintenance. Presented in ideal nutritional potencies and ratios, Cholest-Plex balances cardiovascular wellness via diverse biological pathways, blocking cholesterol absorption and synthesis, promoting blood vessel flexibility, regulating inflammation and enhancing endothelial function.
Our formula supplies 10 mg of policosanol from naturally occuring plant waxes purified from sugar cane. Policosanol has been studied for its role in promoting healthy lipid metabolism, platelet function and antioxidant protection for cardiovascular health. This natural compound may also promote endothelial function and arterial flexibility.
Extracted from pine tree trunks, Phytopin phytosterols supply natural beta sitosterol, sitostanol, and other beneficial plant sterols that have been researched for over 50 years for their ability to promote healthy cholesterol levels. Plant sterols are believed to block absorption of cholesterol in the intestines while promoting healthy production of bile, offering dual-action support for balanced cholesterol levels.
Grape Seed Extract:
Grape seed extract’s vast array of cardio-supportive oligometric proanthocyanidins (OPCs) include catechin, epicatechin, and procyanidin. These antioxidant compounds have 50X the antioxidant activity of vitamin C, and are believed to help promote normal blood pressure, healthy endothelial function, blood vessel integrity, ideal platelet aggregation, and other aspects of vascular wellness. Grape seed extract’s OPC antioxidants also inhibit LDL oxidation and increase resting brachial diameter, suggesting benefits for enhanced circulatory health.
Red Yeast Rice:
Monascus pupureus is used in traditional Asian culture and is extracted into modern red yeast rice supplements for cholesterol support. Red yeast rice is believed to inhibit HMG-CoA reductase while suppressing cholesterol synthesis in the liver. Red yeast rice also supplies potent antioxidant activity to further support blood vessel health and heart health. Numerous studies over the past four decades have demonstrated that red yeast rice preparations are helpful in naturally maintaining blood cholesterol levels already in the normal range.
CoQ10 provides support to all cells throughout the body and is particularly supportive of tissues that require a lot of energy, such as the heart muscle. Coenzyme Q10 is often suppressed in those with cardiovascular conditions, and CoQ10 depletion is often associated with cholesterol-lowering statin drugs. Because there is also evidence that use of red yeast rice can deplete coenzyme Q10, co-supplementation is recommended and CoQ10 is included in this formula.
Antioxidant supplementation can be beneficial for healthy cardiovascular function by decreasing the oxidation of LDL cholesterol. CoQ10 supports cardiac tissues by improving endothelial function and by having an anti-atherogenic effect, promoting lower blood pressure and improved myocardial contractility.