Thirty four million American adults have high cholesterol levels. While synthetic cholesterol drugs can help, they may also sometimes have undesirable side effects, interactions or nutrient depletion issues. Patient One designed Cholest-Plex to be a gentle, well-tolerated natural formula for maintaining cholesterol levels already within a normal range. Cholest-Plex combines evidence-backed natural ingredients in use for millennia with patented advancements for cholesterol control. Presented in ideal nutritional potencies and ratios, Cholest-Plex balances cardiovascular wellness via diverse biological pathways, blocking cholesterol absorption and synthesis, promoting blood vessel flexibility, regulating inflammation and enhancing endothelial function.
A patented blend derived from natural plant waxes, PolicosanolPlus supplies Omega 3-6-9 polyunsaturated fatty acids along with active compounds hexacosanol and octacosanol. PolicosanolPlus has been clinically shown to support healthy blood lipid levels, positively influence beneficial HDL cholesterol, improve LDL processing efficiency, and block biological pathways of cholesterol synthesis. PolicosanolPlus may also promote endothelial function and arterial flexibility, further supporting cardiovascular wellness.
Extracted from pine tree trunks, Phytopin phytosterols supply natural beta sitosterol, sitostanol, and other beneficial plant sterols that have been researched for over 50 years for their ability to promote healthy cholesterol levels. Plant sterols are believed to block absorption of cholesterol in the intestines while promoting healthy production of bile, offering dual-action support for balanced cholesterol levels.
Grape Seed Extract:
Grape seed extract’s vast array of cardio-supportive oligometric proanthocyanidins (OPCs) include catechin, epicatechin, and procyanidin. These antioxidant compounds have 50X the antioxidant activity of vitamin C, and are believed to help promote normal blood pressure, healthy endothelial function, blood vessel integrity, ideal platelet aggregation, and other aspects of vascular wellness. Grape seed extract’s OPC antioxidants also inhibit LDL oxidation and increase resting brachial diameter, suggesting benefits for enhanced circulatory health.
Red Yeast Rice Powder:
Monascus pupureus is used in traditional Asian culture and is extracted into modern red yeast rice supplements for cholesterol support. Supplying natural monacolin compounds, including monacolin K, red yeast rice is believed to inhibit HMG-CoA reductase while suppressing cholesterol synthesis in the liver. Red yeast rice also supplies potent antioxidant activity to further support blood vessel health and heart health. Numerous studies over the past four decades have demonstrated that red yeast rice preparations are helpful in naturally maintaining blood cholesterol levels already in the normal range.
CoQ10 provides support to all cells throughout the body and is particularly supportive of tissues that require a lot of energy, such as the heart muscle. Coenzyme Q10 is often suppressed in those with cardiovascular conditions, and CoQ10 depletion is often associated with cholesterol-lowering statin drugs. Because there is also evidence that use of red yeast rice can deplete coenzyme Q10, co-supplementation is recommended.
Antioxidant supplementation can be beneficial for healthy cardiovascular function by decreasing the oxidation of LDL cholesterol. CoQ10 supports cardiac tissues by improving endothelial function and by having a direct anti-atherogenic effect, leading to lower blood pressure and improved myocardial contractility.