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Omega 800 (120 softgels)

Omega 800 (120 softgels)
gluten free softgel Non GMO Supplement

Ultra-pure Omega-3 fatty acids. Presented in superior triglyceride form in evidence-backed EPA/DHA ratio

  • Promotes creation of fluid cell membranes
  • Helps keep triglycerides and LDL within healthy range
  • Optimizes circulation and blood flow
  • Helps maintain blood pressure already within normal range
  • Promotes healthy levels of C-reactive protein
  • Modulates body’s inflammatory response

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Product Information Sheet (PDF)

Unique Properties

Patient One Omega 800 supplies highly purified and concentrated essential Omega-3 fatty acids in their superior triglyceride form, in an evidenced-backed ratio of 430 mg EPA (eicosapentaenoic acid) and 290 mg of DHA (docosahexaenoic acid), plus a proprietary antioxidant blend.

Certified pharmaceutical grade fish oil sourced from Norwegian cold water fish (anchovy, sardine, mackerel), Omega 800 is molecularly distilled and manufacturer-tested as well as third-party tested for a full range of contaminants and environmental pollutants, including heavy metals, pesticides, dioxins and PCBs. Omega 800 softgels are naturally flavored for a pleasant lemon/lime taste.

Fish oils are rich sources of Omega-3 long-chain polyunsaturated fatty acids. Omega-3 fatty acids EPA and DHA are the two most studied fish oils. Most notably recognized for their beneficial effect on cardiovascular health, Omega-3s have also been shown in studies to be beneficial for brain health, blood pressure support, inflammation modulation, joint health and eye comfort.
 

The "Triglyceride" Form Absorption Advantage

The many health benefits of Omega-3s can only be derived if your body absorbs the fatty acids. Although scientific research demonstrates the triglyceride form as the superior delivery mode of fish oil, very few fish oil concentrates in the marketplace are available in this form because of the higher production costs. Most fish oils contain the “ethyl ester" form of fatty acid, synthetic Omega-3 molecules, shown to be less effective in delivering essential fatty acids to the body during digestion and metabolism. Omega 800 supplies fish oil concentrate in the preferred re-esterified triglyceride form to optimize its effectiveness.


 

Key Ingredients

EPA (eicosapentaenoic acid) and DHA (docosahexaenoic acid):

The majority of Omega-3’s beneficial activities can be traced back to two health-supporting functions in the body—promoting healthy cell membranes and production of eicosanoids.

DHA is an essential component of the phospholipids in human cell membranes, particularly those found in the brain and retina. In clinical studies, Omega-3 fatty acids have demonstrated potential to help maintain healthy triglyceride levels. Additionally, a strong correlation has been shown between fish oil consumption and the ability to maintain healthy levels of C-reactive protein. Fish oils have also been studied for their beneficial role in the maintenance of normal blood flow, as they support normal fibrinogen levels (blood clotting), which contributes to normal platelet activity.

DHA and EPA have various mechanisms of action to help support normal cholesterol and triglyceride levels, help maintain normal blood flow and pressure, and promote normal platelet activity. DHA and EPA help maintain normal triglyceride levels by promoting normal lipogenesis and supporting normal fatty acid oxidation in the liver. DHA and EPA promote the normal transcription of genes coding for lipogenesis enzymes and promote the normal transportation of the regulatory enzymes of fatty acid oxidation.

EPA is a precursor to eicosanoids (TXA3 and LTB5) and an inhibitor of arachidonic acid synthesis of thromboxane A2, which helps to promote normal platelet activity and normal vasodilation. These effects demonstrate EPA’s potential ability to help maintain normal blood pressure and support normal blood clotting. Fish oil may also contribute to the normal production of prostacyclin, a prostaglandin that also promotes normal vasodilation and supports normal platelet activity.

Omega-3 and Omega-6 fatty acids compete metabolically with each other. Omega-6 fatty acids—found in abundance in the typical Western diet—may inhibit the incorporation of Omega-3 fatty acids into tissue lipids. Omega-3s may inhibit the conversion of many Omega-6s into arachidonic acid, often associated with poor heart health. Consuming DHA and EPA Omega-3s appears to help increase these fatty acids while reducing levels of Omega-6 fatty acids to help restore proper lipid balance and support cardiovascular health. 

 

Research

  • The U.S. Physicians’ Health Study unveiled some of the most dramatic evidence supporting the link between Omega-3-rich fish and heart health. In the study, the eating habits of 20,551 healthy male physicians between the ages of 40-84 were tracked over 11 years. Physicians who consumed one fish meal per week were found to be associated with a 52% lower risk of sudden cardiac death when compared with physicians who consumed less than one fish meal per month. Researchers concluded that the prospective data suggest that consuming fish at least once per week may reduce the risk of sudden cardiac death in men. (18)
  • Further research analyzed the blood levels of Omega-3s EPA and DHA in 15,000 U.S. Physicians’ Health Study participants over the course of 17 years. Researchers concluded that men with the highest levels of Omega-3s in their blood showed a 90% reduction in risk for sudden cardiac death compared to those with the lowest levels. (14)
  • Many additional well-designed studies have investigated how Omega-3s impact our cardiovascular system. Among these studies is one that found Omega-3s EPA and DHA make arteries supple and flexible while reducing pulse pressure and total vascular resistance – effects that researchers believe may reduce the risk of adverse cardiovascular events. (17)
  • Another research team conducted a study of 43,000 men aged between 40-75, and discovered that even consuming a small amount of fish (one to three times per month) was associated with a 43% reduction in risk for ischemic stroke. (16) Yet another study’s researchers found that dangerous arrythmias were significantly reduced for 44% of patients who took fish oil. (15)

References

  1. Madsen T, Skou HA, et al, C-reactive protein, dietary n-3 fatty acids, and the extent of coronary artery disease. Am J Cardiol 88:1139-42 (2001)
  2. Rigelsky, JM, et al, Hawthorn: pharmacology and therapeutic uses. Am J Health Syst Pharm 59:417-22 (2002)
  3. Kris-Etherton PM, et al, fish consumption, fish oil, omega-3 fatty acids, and cardiovascular disease.
  4. Arterioscler Thromb Vasc Biol 23(2):e20-e30 (2003)
  5. Morris, MC, Sacks F, Rosner B. Does fish oil lower blood pressure? A meta-analysis of controlled trials. Circulation 88(2):523-533 (19930
  6. Howe PR. Dietary fats and hypertension. Focus on fish oil. Ann NY Acad Sci 827:339-352 (1997)
  7. Morris MC, et al, The effect of fish oil on blood pressure in mild hypertensive subjects: a randomized crossover trial. Am J Clin Nutr 57(1):59-64 (1993)
  8. Knapp HR, FitzGerald GA. The antihypertensive effects of fish oil.
  9. A controlled study of polyunsaturated fatty acid supplements in essential hypertension. J Engl J Med 320(16):1037-1043 (1989)
  10. Bonaa, KH, et al, Effect of eicosapentaenoic and docosahexaenoic acids on blood pressure in hypertension. A population-based intervention trial from the Tromso study. N Engl J Med 322(12):795-801 (1990)
  11. Chan JK, et al, Dietary alpha-linolenic acid is as effective as oleic acid and linoleic acid in lowering blood cholesterol in normolipidemic men. Am J Clin Nutr 53(5):1230-1234 (1991)
  12. Harris WS, et al, Dietary omega-3 fatty acids prevent carbohydrate-induced hypertriglyceridemia. Metabolism 33(11):1016-1019 (1984)
  13. Nestel PJ. Fish oil attenuates the cholesterol induced rise in lipoprotein cholesterol. Am J Clin Nutr 43(5):752-757 (1986)
  14. Tsai PJ, Lu SC. Fish oil lowers plasma lipid concentrations and increases the susceptibility of low density lipoprotein to oxidative modification in healthy men. J Formos Med Assoc 96(9):718-726 (1997)
  15. Garrido A, et al, Ingestion of high doses of fish oil increases the susceptibility of cellular membranes to the induction of oxidative stress.
  16. He K, Rimm E, Merchant A, et al. Fish consumption and risk of stroke in men. The Journal of the American Medical Association 2002; 288:3130-3136.
  17. Nestel P et al. The n-fatty acids eicosapentaenoic acid and docosahexaenoic acid increase systemic arteral compliance in humans. Am J Clin Nutr, 76, 2:326-30,2002.
  18. Alber CM, Hennekens CH, O’Donnell CJ, Ajani UA, Carey VJ. Fish consumption and risk of sudden cardiac death. JAMA 1998; 279:23-7

Supplement Facts

Serving Size: 1 Softgel
Servings Per Container: 120
Amount Per Serving % Daily Value**
Calories 15   <1%
Calories from Fat 10  
Total Fat 1.50 g 2%
Polyunsaturated Fat 1 g
Cholesterol <5 mg <2%
Omega-3 Fatty Acids

Ultra-pure fish oil (trigylcerides)

800 mg
    EPA (Eicosapentaenoic Acid) 430 mg
    DHA (Docosahexaenoic Acid) 290 mg
    Additional Omega-3 Fatty Acids 80 mg
† Daily Value not established.
** Daily Values are based on a 2,000 calorie per day diet.


Suggested Use

Take 1-2 softgels daily as a dietary supplement, preferably with a meal, or as directed by a qualified healthcare professional.

Warnings

Consult with your physician before using this product if you use blood thinners or anticipate surgery. If you are pregnant, nursing, or taking any medications, consult your doctor before use. Discontinue use and consult doctor if any adverse reactions occur.

 
Omega 800 (120 softgels) Label