Berberine is a botanical compound found in plants including barberry, goldenseal, Oregon grape, and tree turmeric. Used in Ayurvedic and Chinese Medicine for hundreds of years, berberine's diverse benefits and mechanisms of action are also supported in modern research. Its primary mechanism is its ability to activate the enzyme Adenosine Monophosphate-Activated Protein Kinase (AMPK) while inhibiting Protein-Tyrosine Phosphatase 1B (PTP1B).
Clinical evidence shows that Berberine may help to support and promote glucose and lipid metabolism. Berberine is also an anti-bacterial and it may help to protect the gastrointestinal system. Further, it promotes cellular antioxidant defense and exhibits anti-inflammatory effects.
Patient One Berberine supplies 500 mg berberine HCl per capsule, the dosage used in clinical trials for glucose and lipid health.