Patient One B-Complex, most commonly recommended for occasional stress, is a blend of 10 essential compounds, including the complete spectrum of B vitamins in their activated and easily absorbable forms, plus related nutrients. Our formula features Quatrefolic®, an advanced, active form of folate. As pre-converted 5-MTHF, Quatrefolic® is ideal for the large portion of the population with a genetic enzyme defect that makes it difficult to convert folic acid into 5-MTHF.
Particularly supportive of proper nervous system function, Patient One’s balanced vitamin B formula helps maintain normal homocysteine levels, supports brain function and provides wide-ranging health benefits.
Thiamine (as Thiamine HCl and Benfotiamine) B1
Patient One B-Complex provides Thiamine as Thiamine HCl along with Benfotiamine—the fat soluble form of Vitamin B-1—to support healthy blood sugar metabolism and protection against advanced glycation and oxidative stress.
Riboflavin (as Riboflavin-5-Phosphate) B2
Readily absorbed in the small intestine but not stored by the body, Riboflavin is an essential B vitamin. Patient One provides Riboflavin in its active form, Riboflavin-5-Phosphate, making it more easily available for use in the body. Riboflavin plays a key role in the conversion of other B vitamins and in fat and glucose metabolism. Riboflavin is also an important nutrient to support healthy eyesight and skin.
Niacin (as Niacinamide) B3
Niacin is an evidence-backed B vitamin that is most commonly used to support cardiovascular wellness. Research has suggested that niacin influences pathways associated with triglycerides and high-density lipoprotein (HDL) cholesterol, helping to maintain blood cholesterol levels that are already within normal range.
Pyridoxine (as Pyridoxal-5-Phosphate) B6
Pyridoxal-5-Phosphate is the metabolically active form of vitamin B-6 that has been shown to protect living lipids and proteins against glycation reactions. Aging results in the formation of advanced glycation end products (AGEs) throughout the body. By inhibiting AGE formation and working as a coenzyme in chemical reactions, pyridoxal-5-phosphate can support healthy nerves, eyes, and cardiovascular and kidney function.
Folate (as Quatrefolic®)
Quatrefolic®, the advanced 5-MTHF (5-methyltetrahydrofolate) form of folate, bypasses metabolic steps for enhanced folate bioavailability. In vitro and in vivo studies have proven that Quatrefolic, the glucosamine salt of 5-MTHF, has greater stability, solubility and bioavailability over calcium salt forms of 5-MTHF. Folic acid is well-known for its critical role in fetal development and also supports cardiovascular health, nervous system health, normal cell growth and energy production. It plays a role in brain energy and helps to promote peak mental sharpness and clear memory.
Vitamin B-12 (as Methylcobalamin)
Methylcobalamin is a highly bioactive form of vitamin B-12 and accounts for most B-12 circulating in plasma. Methylcobalamin B-12 supplies methyl groups for protein and DNA synthesis while supporting circulation, neurotransmitter production, and cellular energy production. B-12 also optimizes healthy homocysteine levels, promoting overall cardiovascular wellness.
Biotin has a beneficial effect on a number of structures and functions in the body. It is best known for its positive effect on hair and nails but also plays a role in supporting glucose metabolism by stimulating glucose-induced insulin secretion in pancreatic beta cells and by accelerating glucose metabolism in the liver.
Pantothenic acid (Vitamin B-5)
Pantothenic acid helps the body convert carbohydrates and fats into energy. It has been clinically proven to have a beneficial effect on lipid metabolism and adrenal immune function. It seems to positively affect triglyceride and lipoprotein levels by producing cystamine. B-5 is also considered the “anti-stress” vitamin because it supports healthy adrenal cortex function and hormone synthesis. In addition, vitamin B5 may support digestive tract health, enhancing absorption of other nutrients.
Choline is an essential nutrient that plays a vital role in maintaining the structural integrity of cell membranes. Choline is a precursor to acetylcholine, an important neurotransmitter involved in memory, muscle control and other essential functions of the body. Choline is needed, along with B vitamins, for methyl group transfer.
PABA (para-aminobenzoic acid)
PABA is a naturally occurring non-protein amino acid that is considered part of the B-Complex family. It supports red blood cell formation, assists in the manufacture of folate (B-9) in the intestines and also assists with breaking down of protein, the formation of red blood cells and maintaining intestinal flora.