• Gluten Free
  • Vegetarian
  • Non-GMO
  • Vegetable Caps

Unique blend of natural ingredients to support cardiovascular health and cholesterol levels already within normal range*

  • Supports healthy lipid metabolism*
  • Optimizes circulation and supports heart health*
  • Promotes blood vessel integrity and flexibility*

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Unique Properties

Patient One formulated Cholest-Plex to be a gentle, well-tolerated natural formula for supporting cholesterol levels already within a normal range. Cholest-Plex provides a complementary combination of natural ingredients including a unique blend of phytosterols, red yeast rice, grapeseed extract, coenzyme Q10, and more.

This formula supports cardiovascular wellness via diverse biological pathways, including supporting blood vessel flexibility and endothelial function, along with promoting lipid metabolism in support of heathy lipid profiles. 



  1. Castano G, et al. Drugs Aging. 2003; 20(2):153-63.
  2. Feringa, H. H., et al. J Am Diet. Assoc. 2011; 111(8):1173-1181.
  3. Shi J, et al. J Med Food. 2003; 6(4):291-9.
  4. Mellen P, et al. J Am Coll Nutr. 2010; 29(5):469-47
  5. Malinowski JM, et al. Am J Health Syst Pharm. 2010; 67(14):1165-73.
  6. Leifert WR, et al. Nutr Res. 2008; 28(11):729-37.
  7. Cicero AFG, et al. Complement Ther Med. 2005; 13(4):273-278.
  8. Becker DJ, et al. Ann Intern Med. 2009; 150(12):830-09.
  9. Bianchi A. Chin J Integr Med. 2005; 11(4):309-13.
  10. Wang TH, et al. Adv Food Nutr Res. 2007; 53:123-59.
  11. Molyneux SL, et al. N Z Med J. 2009; 122(1305):74-79.
  12. Soukoulis V, et al. J Am Coll Cardiol. 2009; 54(18):1660-73.

Supplement Facts

Serving Size: 2 Capsules
Servings Per Container: 60
Amount Per Serving % Daily Value**
Pantethine (Pantesin®) 50 mg
Red Yeast Rice powder

(Monascus purpureus) (seed) 

600 mg

(from sugar cane wax)

10 mg
Grapeseed extract

(Vitis vinifera) (inner core of fruit) [Standardized for 95% proanthocyanidins (47.5 mg)] 

50 mg
Coenzyme Q10


30 mg

 [as Phytopin® Pine Extract 99% sterols)[Typical Profile provides: Beta-Sitosterol 70-80% (210-240 mg), Beta-Sitostanol NMT 15% (45 mg), Campesterol 6-10% (18-30 mg), Campestanol NMT 2% (6 mg), Other Phytosterols NMT 3% (9 mg)]

300 mg
† Daily Value not established.

Suggested Use

Take 2 capsules as a dietary supplement, preferably with a meal, or as directed by your health practitioner.


Do not use if you are allergic to rice or if you are pregnant or nursing. Consult your health practitioner before use if taking any cholesterol, blood thinning or other medications. Do not use if you have kidney or liver disease. Discontinue use if you experience any unexplained muscle pain, weakness or rash. Discontinue use and consult health practitioner if any adverse reactions occur. Keep out of reach of children. Use only if safety seal is intact.

Cholest-Plex Label