Berberine 500 mg

Berberine 500 mg
  • Gluten Free
  • Vegetarian
  • Non-GMO
  • Vegetable Caps

Multi-faceted botanical compound that supports healthy glucose metabolism, cardiovascular wellness, gut health and more*

  • Promotes enhanced glucose and insulin metabolism*
  • Helps maintain cholesterol levels already in a normal range*
  • Supports healthy metabolic function*
  • Promotes intestinal health*

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Berberine is a botanical compound found in plants including barberry, goldenseal, Oregon grape, and tree turmeric. Used in Ayurvedic and Chinese herbal practices for hundreds of years, berberine's diverse mechanisms of action are also supported in modern research.

Its primary mechanism is its ability to activate the enzyme Adenosine Monophosphate-Activated Protein Kinase (AMPK), a central regulator of cellular energy homeostasis, while inhibiting Protein-Tyrosine Phosphatase 1B (PTP1B), a negative regulator of the leptin and insulin signaling pathways.



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  8. Zhang Y, et al. J Clin Endocrinol Metab. 2008;93(7):2559-2565.

Supplement Facts

Serving Size: 1 Capsule
Servings Per Container: 60
Amount Per Serving % Daily Value**
Berberine Hcl

(from Indian Barberry extract) (Berberis aristata root) 

500 mg
† Daily Value not established.

Suggested Use

Take 1 capsule 1-2 times daily as a dietary supplement, preferably with a meal or shortly after, or as directed by a health practitioner. Store in a cool, dry place.


If pregnant, nursing, or trying to conceive, do not use this product. Consult your health practitioner before use if taking any medications. Discontinue use and consult your health practitioner if any adverse reactions occur. Keep out of reach of children. Use only if safety seal is intact.

Berberine 500 mg Label