Patient One Q-Folate supplies 800 mcg of Quatrefolic®, the glucosamine salt of (6S)-5 methyltetrahydrofolate (5-MTHF), proven to have greater stability, solubility, and bioavailability over calcium salt forms of 5-MTHF and over supplementation with folic acid.
Folate is noted for its important role in fetal development, but the benefits of this essential B vitamin extend beyond healthy pregnancy and women’s reproductive health. Folate supports cardiovascular health, nervous system health, normal cell growth and energy production. It also plays a role in brain energy and helps to promote mental sharpness. Folate serves as a donor of methyl groups in many nervous system and metabolic processes including the conversion of homocysteine to methionine, the synthesis of monoamine neurotransmitters (serotonin, dopamine and epinephrine), the production of melatonin, and the synthesis of DNA.
Folic acid must be converted to its active form, 5-MTHF, which takes four separate biochemical reactions in the intestines and liver, in order for the body to absorb and utilize it.
A significant percentage of the U.S. population may have a genetic enzyme defect that makes it difficult for them to convert folic acid into active 5-MTHF, making this pre-converted, biologically active form of folate the preferred, universally metabolized form.
Absorption of folate is believed to decline with age. Patient One’s Q-Folate helps overcome this challenge, supplying folate in a highly absorbable form for populations of all ages.