Gluten Free
Non-GMO
Vegan
Vegetable Caps

Pycnogenol® OPC Complex 300 mg (30 caps)

Nutritional support for peak vitality across multiple body systems and free radical defense for overall healthy aging*

Reduces oxidative damage to vital tissues*
Supports vascular function*
Increases nitric oxide production*
Promotes healthy inflammatory response*
Supports joint mobility and flexibility*

Patient One Pycnogenol® OPC Complex 300mg is a potent super antioxidant formula comprised of multiple OPC’s (Oligomeric Proanthocyanidins) — powerful bioflavonoids that act as free radical scavengers in the human body and promote antioxidant activity and overall healthy aging. This highly absorbable formula features a network of clinically proven antioxidant compounds with a diverse spectrum of demonstrated health and wellness support functions: promoting heart health, normalizing blood vessel diameter, protecting retinal capillaries, promoting clear respiration, encouraging healthy inflammatory response, supporting youthful and healthy skin, and more.

Key Ingredients

Pycnogenol® French Maritime Pine Bark is one of the most evidence-based natural ingredients in the world, with over 220 scientific publications on its safety and efficacy across a variety of areas of health. Considered a “super antioxidant,” Pycnogenol binds to collagen and elastin, influencing endothelial nitric oxide production, which may promote healthy circulation as well as a vasodilation effect that may also support healthy blood pressure already within a normal range. Pycnogenol supports the immune system and modulates the body’s inflammatory response while increasing skin elasticity and protecting against UV damage.

Mirtoselect® Bilberry Extract, another extensively studied OPC, provides 36% anthocyanins—antioxidants that act as potent scavengers of free radicals that have demonstrated support for a broad range of health benefits. Mirtoselect has been found to be effective in supporting retinal sensitivity and visual acuity, venous health, blood sugar stabilization and healthy inflammatory response.

Grapeseed Extract in our formula is standardized to 95% total pro-anthocyanidins, and supplies beneficial compounds and antioxidants from California-grown red and white wine grape seeds. By including lower molecular weight OPCs, bioavailability and absorption is improved — optimizing grapeseed’s support for blood vessels and promoting healthy circulation.

Red Wine Extract, standardized to 25% polyphenols, supplies additional high-potency antioxidants. Evidence supports the protective contribution of polyphenols in cardiovascular and bone health and suggests their defensive role in nervous system health and blood glucose metabolism support.

Citrus Bioflavonoids are derived from fruits high in vitamin C, and they appear to act synergistically with the vitamin to neutralize free radicals. Antioxidant properties of bioflavonoids are thought to be particularly beneficial for capillary strength.

References

Devaraj S., et al. Lipids. 2002; 37(10):931-934.
Fitzpatrick DF, et al. J Cardiovasc.Pharmacol. 1998; 32(4):509-515.
Campbell F.M., et al. Proceedings of the Nutrition Society. 2012; (71) (OCE2), E130.
Grimm T, et al. J Inflamm. 2006; 3:1-6.
Hosseini S, et al. Nutr Res. 2001; 21:1251-1260.
Kajimoto S. J. New Rem. Clin. 2000; 49, 72-79.
Koch R. Phytother Res. 2002; 16:1-5.
Mian E. Minerva Med. 1977; 68(52): 3565-3581.
Moini H. et al. Methods Enzymol. 2001; 335:333-7.
Nishioka K. et al. Hypertens Res. 2007; 30:775-780.
Park YC. et al. FEBS Lette. 2000; 465(2-3):93-7.
Rohdewald P. Eur Bull Drug Res. 1999; 7:14-18.
Sandhagen B. Clin Hemorheol Microcirc. 1999; 21(3-4):179-81
Schafer A. et al. Biomed. Pharmacother. 2006; 60(1):5-9
Sivonova M, et al. Gen. Physiol. Biophys. 2004; 23:39-5
Watson RR. Evid Based Integrative Med. 2003; 7-32.

Supplement Facts

Serving Size: 1 Capsule
Servings Per Container: 30
Amount Per Serving	% Daily Value**

Pycnogenol® (French Maritime Pine Bark Extract)	100	mg	†
Grapeseed extract (Vitis vinifera) (inner core of fruit) [Standardized for 95% proanthocyanidins (47.5mg)]	50	mg	†
Red wine extract (Vitis vinifera) (skin) [Standardized for 25% polyphenols (12.5mg)]	50	mg	†
Mirtoselect® Bilberry fruit (Vaccinium myrtillus L.) [Standardized ethanolic extract 36% of anthocyanins (18mg)]	50	mg	†
Citrus bioflavonoid complex Standardized to 50% bioflavonoids (25mg) [Proprietary blend of Flavanone (Hesperidin) and Flavonones (Naringin, Naringenin 7-B-Rutinoside and others)]	50	mg	†

† Daily Value not established.
Other Ingredients: Vegetable cellulose (capsule), rice flour, leucine
This product contains NO milk, eggs, fish, peanuts, crustacean shellfish, soy, treenuts, wheat and yeast. This product is free of ingredients derived from genetically modified organisms (GMOs).
Trademarks:

Suggested Use

Take 1 vegetarian capsule daily as a dietary supplement, between meals, or as directed by your health practitioner. Store in a cool, dry place.

Warnings

If you are pregnant, nursing, or taking any medications, consult your health practitioner before use. Discontinue use and consult health practitioner if any adverse reactions occur. Keep out of reach of children. Use only if safety seal is intact.