B-Complex with Quatrefolic®

B-Complex with Quatrefolic®
  • Gluten Free
  • Vegetarian
  • Non-GMO
  • Vegetable Caps

Active essentials for cellular energy production, nervous system function and cardiovascular health*

  • Broad spectrum B vitamin support*
  • Protects against stress-induced nutrient depletion*
  • Supports healthy methylation*
  • Promotes mental clarity, memory, and focus*
  • Optimizes new cell growth*

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Unique Properties

Patient One B-Complex, most commonly recommended for occasional stress, is a blend of 10 essential compounds, including the complete spectrum of B vitamins in their activated and easily absorbable forms, plus related nutrients.

Our formula features Quatrefolic®, an advanced, active form of folate. As pre-converted 5-MTHF, Quatrefolic® is ideal for the large portion of the population with a genetic enzyme defect that makes it difficult to convert folic acid into 5-MTHF.  Folate, along with B6 and B12, are required for proper methylation, a biochemical process that helps convert the problematic amino-acid-metabolite homocysteine into the amino acids methionine and cysteine. Proper methylation is critical for supporting many aspects of mental and physical health, including regulating gene expression and DNA repair.

Adequate B vitamin levels are essential for maintaining energy levels and additional intake is often needed by those with high levels of stress. A variety of B vitamins is essential for the body to convert food into cellular energy. These water-soluble vitamins are absorbed in the small intestine and then travel to the liver where they are biotransformed into their coenzyme forms. One of the key roles of B vitamins is to serve as prime coenzymes for the Kreb’s cycle, the biochemical pathway responsible for maintaining energy production in the form of cellular energy.

Particularly supportive of proper nervous system function, B vitamins support neurotransmitter production to help promote a positive mood.



  1. Willems FF, et al. Br J Pharmacol. 2004; 41(5):825-30
  2. Stirban A, et al. Diabetes Care. 2006; 29(9):2064-71. Nature Med. 2003; 9(3):294-9.
  3. Schnyder G, et al. N Engl J Med. 2001; 345:1593-1600.
  4. Halsted CH, et al. Alcohol. 2002; 27(3):169-72.
  5. Yakut M, et al. Eur J Intern Med. 2010; 21(4):320-23.

Supplement Facts

Serving Size: 1 Capsule
Servings Per Container: 60
Amount Per Serving % Daily Value**

Vitamin B-1 (Thiamine HCI)

87.50 mg 7,292%

Riboflavin (Vitamin B-2) (as Riboflavin-5-Phosphate)

25 mg 1,923%

Niacin (Vitamin B-3) (as niacinamide)

75 mg 469%

Pyridoxine (Vitamin B-6) (as Pyridoxal-5-Phosphate)

25 mg 1,471%

Folate (as Quatrefolic® [6S]-5-Methyltetrahydrofolic acid equivalent to 800 mcg of [6S]-5-Methyltetrahydrofolic acid, glucosamine salt)

666 mcg 167%

Vitamin B-12 (as methylcobalamin)

400 mcg 16,667%


300 mcg 1000%

Choline (from Choline Bitartrate)

20 mg 4%

Pantothenic acid (Vitamin B-5) (as D-calcium pantothenate) 

100 mg 2,000%
PABA (para-aminobenzoic acid) 25 mg
Benfotiamine 18 mg
† Daily Value not established.
** Daily Values are based on a 2,000 calorie per day diet.

Suggested Use

Take 1 capsule as a dietary supplement, preferably with a meal, or as directed by your health practitioner. Store in a cool, dry place.


If you are pregnant, nursing, or taking any medications, consult your health practitioner before use. Discontinue use and consult your health practitioner if any adverse reactions occur. Keep out of reach of children. Use only if safety seal is intact.

B-Complex with Quatrefolic® Label