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Homocysteine Cardioplex

Homocysteine Cardioplex

Helps maintain normal homocysteine levels for optimal cardiovascular well-being*

  • Modulates homocysteine’s metabolic pathways*
  • Supports homocysteine conversion into methionine and cysteine*
  • Optimizes endothelial health and function*
  • Gluten Free
  • Non-GMO
  • Vegetable Caps

$33.50 MSRP

Patient One Homocysteine Cardioplex supplies broad-spectrum nutritional support for maintaining homocysteine levels already within normal range. High homocysteine levels are linked to increased risk as a cardiovascular health marker. Homocysteine Cardioplex supplies highly absorbable and bioavailable forms of key B vitamins along with diverse methyl donor nutrients. As it opens multiple pathways for catalyzing homocysteine  remethylation to methionine, this formula balances plasma homocysteine levels and promotes overall cardiovascular wellness.

Key Ingredients

A reduced and active form of folate (vitamin B-9), Quatrefolic®, the advanced 5 methyltetrahydrofolate (5 MTHF) form, is bound with natural glucosamine salt to promote easy and complete absorption. Quatrefolic is shown to be significantly more stable and bioavailable than 5 MTHF that is bound to calcium salt. Quatrefolic’s pre-converted status may be especially beneficial for those with a genetic defect of the folate-converting enzyme methylentetrahydrofolate reductase.

Supplying vitamins B-6 (as pyridoxal-5-phosphate) and B-12 (as Methylcobalamin), Homocysteine Cardioplex provides two extensively researched clinical standards for nutritional homocysteine management. B-6 modulates homocysteine’s conversion into cysteine, a key step in its excretion. B-12 is an important donor for enabling homocysteine to be remethylated into methionine. B-12 also works in concert with the coenzyme methionine synthase, creating a primary pathway of remethylation of homocysteine.

N-Acetyl L-Cysteine (NAC) is a free-form amino acid and precursor to glutathione, the body’s most powerful antioxidant. It is believed to hinder formation of homocysteine at plasma protein binding sites while encouraging efficient elimination of homocysteine via urinary excretion. As it works to promote healthy endothelial function, NAC offers further support for overall cardiovascular health.

Trimethylglycine, also known as betaine, is considered a key player in homocysteine metabolism and has long been administered as a methyl donor for remethylating homocysteine back into methionine. Trimethylglycine (TMG) betaine is a necessary cofactor in the secondary pathway of homocysteine metabolism.

The Real Amino Acid Chelate System, also known as TRAACS®, is a patented range of proprietary mineral amino acid chelates. TRAACS magnesium (Magnesium Glycinate Chelate Buffered Powder) is an organic mineral form known for its ease of absorption. Featuring a biological advantage in assimilation, TRAACS requires no conversion: It is an active cofactor for promoting effcient homocysteine-to-methionine conversion. Research also suggests magnesium may support arterial health and play a role in modulating production of the destructive MMP-2 enzyme, which has been linked with homocysteine issues and collagen degradation.


 

 

 

References

  1. Collaboration HLT. Br Med J. 1998; 316(7135):894–898.
  2. Guo H, et al. Circ J. 2006; 70(1):141-6.
  3. Yilmaz H, et al. Acta Cardiol. 2007; 62(6):579-85.
  4. Hultberg B, et al. Scand J Clin Lab Invest. 1994; 54(6):417-22.
  5. Ventura P, et al. Pharmacol Res. 1999; 40(4):345-50.
  6. Wilcken DE, et al. N Engl J Med. 1983; 309(8):448-53.
  7. Wilcken DE, et al. Ann N Y Acad Sci. 1998; 854:361-70.
  8. Alfthan G, et al. Br J Nutr. 2004; 92(4):665-9.
  9. Venn BJ, et al. Am J Clin Nutr. 2003; 77(3):658-62.
  10. Streenge G, et al. J Nutr. 2003; 133(5):1291-1295.

Supplement Facts

Serving Size: 3 Capsules
Servings Per Container: 30
Amount Per Serving % Daily Value**

Vitamin B-6 (as pyridoxal-5-phosphate)

 100 mg 5882%

Folate [as Quatrefolic® (6S)-5-Methyltetrahydrofolic acid equivalent to 1600 mcg of (6S)-5-Methyltetrahydrofolic acid, Glucosamine Salt]

 1333 mcg 333%

Vitamin B-12 (as Methylcobalamin)

 500 mcg 20833%

Magnesium (as TRAACS® Magnesium Glycinate Chelate Buffered with Magnesium Oxide)

 150 mg 38%
N-Acetyl-L-Cysteine 600 mg †
Trimethylglycine (as betaine anhydrous) 500 mg †
† Daily Value not established.
** Daily Values are based on a 2,000 calorie per day diet.
Other Ingredients:

Vegetable cellulose (capsule), microcrystalline cellulose, leucine

This product contains NO milk, egg, fish, peanuts, crustacean shellfish, soy, tree nuts, wheat, yeast and gluten.

This product is free of ingredients derived from genetically modified organisms (GMOs).



Suggested Use

Take 3 capsules daily, in divided doses with meals, as a dietary supplement or as directed by your health practitioner. Store in a cool, dry place.

Warnings

If you are pregnant, nursing, or taking any medications, consult your health practitioner before use. Discontinue use and consult doctor if any adverse reactions occur. Keep out of reach of children. Use only if safety seal is intact.

 
Homocysteine Cardioplex Label


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