Vitamin C 1000 with Bioflavonoids

Vitamin C 1000 with Bioflavonoids
  • Gluten Free
  • Vegetarian
  • Non-GMO

Clinically proven and patented form of Vitamin C that is rapidly absorbed, plus citrus bioflavonoids for enhanced effectiveness

  • Formulated with naturally derived lipid metabolites (fatty acids from vegetable wax) to enhance bioavailability
  • Potent antioxidant and free radical scavenger
  • Provides immune defense
  • Promotes vascular and endothelial health
  • Assists with iron absorption and red blood cell formation

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Product Information Sheet (PDF)

Unique Properties

Patient One Vitamin C 1000 supplies 1000 mg of all natural C-lipid metabolites, along with 200 mg of citrus bioflavonoids. As Vitamin C is a water soluable vitamin that the body does not make or store, our formula uses a special delivery system that allows the vitamin C to be more rapidly absorbed and retained by the body. Ascorbic acid is combined with lipid metabolites, fat-soluble compounds that increase vitamin C’s function in the body. Bioflavonoids, polyphenolic compounds found in plants such as vitamin C-rich citrus fruit, are included to complement the activities of Vitamin C.

Sufficient intake and retention is necessary to maintain vitamin C status in the body. Factors that increase the human requirement for this essential nutrient include stress, smoking, pollution, radiation and heavy metal exposure, and immune challenges. The Institute of Medicine has recommended an increase in Vitamin C requirements for smokers due to their exposure to toxins and oxidative elements in cigarette smoke.

Role of Vitamin C and Citrus Bioflavonoids

Vitamin C supports a diverse range of bodily functions, including immune stimulation and protection, vascular function and synthesis of collagen, carnitine, and neurotransmitters. It is used in the growth and repair of tissue throughout the body and is a powerful antioxidant that helps neutralize free radicals.

Vitamin C has been widely studied and is commonly known for its role in moderating the severity or duration of acute immune challenges. It appears to heighten the immune response to infections, impacting T-cell proliferation. This nutrient also plays a role in the deactivation of histamine.

The essential role of vitamin C in the formation of collagen makes it crucial in maintaining skin, gum, capillary, joint and skeletal health. Vitamin C is important in energy production, as synthesis of carnitine is dependent upon this nutrient. Because it is necessary for the conversion of dopamine to norepinephrine, Vitamin C assists in maintaining healthy mood and brain function. Supplementation with vitamin C also appears to help reduce inflammation and inflammatory biomarkers, particularly circulating C-reactive protein (CRP).

Our formula includes citrus bioflavonoids, phytonutrients that are vital for proper absorption of Vitamin C. Studies have shown their ability to enhance and prolong the action of vitamin C. 


  • Comparative research studies in vitro and in humans demonstrate that this patented form of vitamin C is more rapidly absorbed and leads to higher plasma and cellular levels, having faster and more beneficial effects than ascorbic acid, calcium ascorbate and other ascorbate products. These benefits include better stimulation of neurite outgrowth, increased fibroblast wound healing activities, increased protection of the immune system from xenobiotic induced inflammatory mechanisms, and greater reduction of plasma levels of C-reactive protein and oxidized LDL, as well as more potent antioxidant and free radical scavenging capabilities. [Med Sci Monit 2007;13(3): BR51-58; Med Sci Monit 2007: 13(10) and additional unpublished studies]


  1. A novel vitamin C preparation enhances neurite formation and fibroblast adhesion and reduces xenobiotic-induced T-cell hyperactivation.Med Sci Monit, 2007; 13(3): BR51-58). PMID: 17325628
  2. Weeks BS, Perez PP. Absorption rates and free radical scavenging values of vitamin C-lipid metabolites in human lymphoblastic cells. Med Sci Monit. 2007;13(10):BR205-210. PMID: 17901843
  3. Vinson, J.A. & Bose, P. Comparative bioavailability to humans of ascorbic acid alone or in a citrus extract. American Journal of Clinical Nutrition. 1988; volume 48: pages 501-604. PMID: 3414575
  4. Wintergerst ES, Maggini S, Hornig DH. Immune-enhancing role of vitamin C and zinc and effect on clinical conditions. Ann Nutr Metab. 2006;50(2):85-94. [PMID: 16373990]
  5. Hemila H, Douglas RM. Vitamin C and acute respiratory infections. Int J Tuberc Lung Dis. 1999 Sep;3(9):756-61.
  6. NIH Office of Dietary Supplements. Dietary Supplement Fact Sheet: Vitamin C.
  7. MacKay D, Miller AL. Nutritional support for wound healing. Altern Med Rev. 2003 Nov;8(4):359-77. [PMID: 14653765]
  8. Linus Pauling Institute. Vitamin C. http://lpi.
  9. Johnston CS. The antihistamine action of ascorbic acid. Subcell Biochem. 1996;25:189-213. [PMID: 8821975]
  10. Strohle A, Wolters M, Hahn A. Micronutrients at the interface between in ammation and infection—ascorbic acid and calciferol: part 1, general overview with a focus on ascorbic acid. In amm Allergy Drug Targets. 2011 Feb;10(1):54-63. [PMID: 21184650]
  11. Hemila, Harri. "Vitamin C And Plasma Cholesterol." Food Science and Nutrition (1992): 33-57.
  12. Ginter, Emil. "Marginal Vitamin C Deficiency, Lipid Metabolism, and Atherogenesis." Advances in Lipid Research (1978): 167-220.
  13. Afkhami-Ardekani, Mohammad, and Ahmad Shojaoddiny-Ardekani. "Effects of Vitamin C on Blood Glucose, Serum Lipids and Serum Insulin in Type 2 Diabetes Patients." Indian J Med Research (2006): 471-74.
  14. Pancorbo, Dario, Carlos Vazquez, and Mary Ann Fletcher. "Vitamin C-lipid Metabolites: Uptake and Retention and Effect on Plasma C-reactive Protein and Oxidized LDL Levels in Healthy Volunteers." Medical Science Monitor
  15. Ginter, Emil. "Vitamin C Deficiency, Cholesterol Metabolism and Atherosclerosis." Institute of Preventative and Clinical Medicine (n.d.): 166-73.

Supplement Facts

Serving Size: 1 Tablet
Servings Per Container: 90
Amount Per Serving % Daily Value**

Vitamin C [from proprietary formulation of ascorbic acid USP combined with lipid metabolites (fatty acids) from vegetable waxes]

1000 mg 1111%
Citrus Bioflavonoid Complex

[50% total bioflavonoids]

200 mg
† Daily Value not established.
** Daily Values are based on a 2,000 calorie per day diet.

Suggested Use

Take 1 tablet one to two times daily, in divided does preferably with meals, as a dietary supplement or as directed by your health practitioner. Store in a cool, dry place.


If pregnant, nursing or taking any medications, consult your health practitioner before use. Discontinue use and consult your health practitioner if any adverse reactions occur. Keep out of reach of children. Use only if safety seal is intact.

Vitamin C 1000 with Bioflavonoids Label