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NeuroOne™
NeuroOne™
  • Gluten Free
  • Vegetarian
  • Non-GMO
  • Vegetable Caps

Comprehensive, multi-modal support for cognitive performance, supplying nutrition for neurogenesis, cerebral circulation and antioxidant activity in the brain.*

  • Healthy focus, memory, clarity and mood*
  • Promotes neurogenesis and brain energy*
  • Optimizes neurotransmitter production*
  • Supports healthy cerebral circulation*

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Patient One NeuroOne™ supplies comprehensive brain-boosting nutrients to activate serotonn (5HT-1a) receptors, promote healthy cerebral blood flow, support neurotransmitter production, help protect brain cells from oxidative stress, and supply vital building block nutrition for neurogenesis - the creation of new brain cells. NeuroOne is an ideal formula for optimizing cogntive function, whether supporting mental focus and attention span or promoting bright mood and addressing mild memory problems associated with aging.

 

Key Ingredients

Acetyl-L-Carnitine (ALC) is found naturally in the body and readily crosses the blood-brain barrier. It promotes healthy nerve cell function by maintaining normal mitochondrial bioenergetics and stabilizing cell membranes, to support emotional health and mental function.

ALC also contributes to the production of acetylcholine, an important neurotransmitter that plays a role in learning, memory and attention. This nutrient also supports the brain’s natural defenses against free radical attack.

Citocholine, a naturally occurring nutrient found in the healthy brain, is the most well-studied choline agent precursor. Choline precursors promote healthy growth of cell membranes. Citocholine helps support the brain’s metabolic activity and has a variety of neuro-protective and neuro-regenerative properties. This brain health nutrient is an essential building block for certain key neurotransmitters that promote focus, attention and memory.

Sharp-PS® Phosphatidylserine supplies soy-free, sunflower lecithin-derived phosphatidylserine (PS). The most abundant phospholipid in the brain, PS is a structural component of cells that is vital for neuron function. The human body contains about 30 g of phosphatidylserine, about half of which is found in the brain.

PS is a raw material in neurogenesis, the creation of new brain cells. It promotes brain cellular energy and catalyzes neurotransmitter production, promoting communication between brain cells. Because neuronal cells do not readily regenerate, it is important that these cells have a superior survival mechanism. High levels of PS in neuronal membranes were shown to be important for neuronal survival.

BaCognize® Bacopa monnieri: Brewed concoctions containing Bacopa monnieri (Brahmi) have long been a part of daily life for children and adults in India. Bacopa extracts are widely used in integrative practices to assist with cognitive function.

BaCognize® is a proprietary, concentrated extract of Bacopa monnieri which has undergone rigorous scientific validation. Clinical research indicates Bacopa offers broad benefits for cognitive health, linked to three major neuro-supportive mechanisms: neurotransmitter receptor binding activity, antioxidant capacity and inflammatory response modulating. Standardized to 45% baccosides, Bacognize has shown activity at the site of human serotonin receptors and has been shown to promote cognitive performance, working memory and mood. It may help address fuzzy thinking and forgetfulness.

Ginkgo Biloba: Neurons are completely reliant on a continuous supply of oxygen and glucose, which is delivered to them by the blood. Neurological tissue is especially vulnerable to oxidative stress because of its high demand for oxygen, high levels of polyunsaturated fatty acids in neural membrane phospholipids, and low antioxidant defenses. This antioxidant botanical enhances cerebral blood circulation and cerebral oxygenation, supporting healthy brain energy and optimizing delivery of NeuroOne’s neuro-nutrient complex.
 

References

  1. Nathan P.J., et al. Human Psychopharmacol. Clin. Exp. 2004; 19:91-96.
  2. Psychology Department of Lady Amritabai Daga College for Women, Nagpur, India.
  3. Hall B, et al. Am. Soc. Pharmacog. 2005; Absts. 85, 83.
  4. Roodenrys S, et al. Neuropsychopharmacology. 2002; 27(2):279-281.
  5. Wells K, et al. Springer Netherlands. 1995; 20(11);1329-33.
  6. Parietti L, et al. Mech Aging Dev. 2001; 122:2045-55.
  7. Fernandez-Murray JP, et al. J Biol Chem. 2005; 280:38290-6.
  8. Moreno D. Clin Ther. 2003; 25:178-93.
  9. Crook T, et al. Psychopharmacol Bull. 1992; 28(1):61-6.
  10. Singh, M. Indian Journal of Pediatrics. 2005; Vol.72, Issue 3, 239-242.
  11. Barberger-Gateau P, et al. British Medical Journal. 2002; 325:932-933.
  12. Schaefer E, et al. Arch Neurol. 2006; 63:1545-1550.
  13. Tabaton M, et al. Ital J Neurol Sci. 1986; 7(1):161-163.
  14. Chrissobolis S, et al. Trends Mol Med. 2008; 14(11):495-502.
  15. Cherix et al. eLife. 2020; 9:e50631.
  16. Cristofano A, et al. PLoS ONE. 2016; 11(5):e0155694.
  17. Kiminori M, et al. Bioscience, Biotechnology, and Biochemistry. 2018; 82(4):647-653
  18. Wang S. et al. Med Sci Monit, 2020; 26:e920250
  19. Jasielski P, et al. Nutrients. 2020; 12(10):3113.

Supplement Facts

Serving Size: 2 Capsules
Servings Per Container: 30
Amount Per Serving % Daily Value**
Acetyl-L-Carnitine (from HCl) 300 mg †
Citocholine (cytidine 5'-diphosphocholine) 200 mg †
Phosphatidylserine (as Sharp-PS® Phosphatidylserine, from sunflower) 100 mg †

Bacognize® (Bacopa monnieri) (whole-herb extract) [Std. to 45% bacosides (135 mg) and 12% total bacopa glycosides (36 mg)]

 300 mg †

Ginkgo biloba (leaf) extract [Std. for 24% ginkgoflavonglycosides (14.4 mg) and 6% total terpene lactones (3.6 mg)]

 60 mg †

Proprietary Blend: Perluxan® Hops Std. Extract (Humulus lupulus L.) (cones), Ginger Root Std. Extract (Zingiber officinale) (rhizome), Spanish Rosemary Extract (Rosmarinus officinalis) (leaves), Grapeseed extract (Vitis vinifera) (inner core of fruit) [Std. for 95% proanthocyanidins], trans-Resveratrol (from Polygonum cuspidatum extract) and Quercetin (as Quercetin dihydrate)

 30 mg †
† Daily Value not established.
** Daily Values are based on a 2,000 calorie per day diet.
Other Ingredients:

vegetable cellulose, rice flour, calcium palmitate, silica

Made with ingredients that are free of: milk, egg, fish, peanuts, crustacean shellfish, soy, tree nuts, wheat, yeast, gluten, sesame and GMOs.

Trademarks:

Sharp-PS® Green is a registered trademark of Enzymotec Ltd. Bacognize® is a registered trademark of Verdure Sciences. Perluxan® is a registered trademark of Pharmachem Laboratories.



Suggested Use

Take 2 capsules once daily as a dietary supplement, or as directed by your health practitioner. Store in a cool, dry place.

Warnings

If pregnant, nursing, or taking blood thinners or other medications, consult your health practitioner before use. Discontinue use and consult your health practitioner if any adverse reactions occur. Keep out of reach of children. Use only if safety seal is intact.

 
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